Oncology Times is pleased to report on the latest groundbreaking research presented at the AACR 2018 Annual Meeting, Chicago, IL. 

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New! Evaluating Nivolumab + Ipilimumab vs. Standard Chemo in NSCLC

Lung cancer is the greatest cause of cancer death worldwide and for most patients with newly diagnosed advanced non-small cell lung cancer (NSCLC), chemotherapy has long been the standard.

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Evaluating Chemotherapy & Pembrolizumab in Metastatic NSCLC

For patients having advanced non-small cell lung cancer (NSCLC) without any targetable mutations, the first-line therapy is platinum-based chemotherapy.

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Research Recap: Hot Topics From AACR Annual Meeting 2018

More than 22,500 attendees from over 70 countries came together in Chicago last week for the AACR Annual Meeting 2018.

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Precancerous Colon Polyps in Patients With Lynch Syndrome Exhibit Immune Activation

Colon polyps from patients with Lynch syndrome, a hereditary condition that raises colorectal cancer risk, display immune system activation well before cancer development, according to research from The University of Texas MD Anderson Cancer Center, Houston.

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Immunotherapy Shows Promise Among Lung Cancer Patients

Advances in immunotherapy continue to confirm the power of harnessing the immune system in the treatment of cancer patients.

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Prior Chemotherapies Impair CAR T-Cell Production

Prior chemotherapies may impair the ability to develop effective chimeric antigen receptor (CAR) T cells to treat children with solid tumors

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Pembrolizumab Shows Reduced Risk for Recurrence in Completely Resected Stage III Melanoma

A 1-year course of 18 doses of adjuvant pembrolizumab was shown to significantly reduce the risk of recurrence for stage III melanoma patients that were at high risk of recurrence after surgery.

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Vulnerable Populations Lack Information About Clinical Trials & Biobanking

People who experience cancer health disparities are interested in participating in clinical trials or submitting samples to biobanks if they receive this information from a trusted physician.

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Risk of Cancers Increased Among Children With Non-Chromosomal Birth Defects

A recent study suggests that children with non-chromosomal birth defects had a significantly higher risk of developing childhood cancer than those who did not have birth defects.

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Prior Chlamydia Infection Doubles Risk of Ovarian Cancer

Prior infection with the sexually transmitted disease chlamydia may double the risk of ovarian cancer, suggesting a potential way to reduce the risk of ovarian cancer through targeted treatment of chlamydia infections, according to a new study.

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Mutations Confer Resistance to Hormone Therapy in Metastatic Breast Cancer

Acquired HER2 mutations confer resistance to hormone therapy in some ER-positive metastatic breast cancer patients. 

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